This study was to establish the impact of ICT on e-learning in Public Secondary Schools in Githunguri Sub-County. The study was guided by the following specific objectives; To establish the linkage between communication through ICT and e-learning in Public Secondary Schools in Githunguri Sub-County; To establish the outcome of ICT in learning in Public Secondary Schools in Githunguri Sub-County; To establish factors influencing e-learning in Githunguri Sub-County. This study was a survey and was conducted using descriptive research design. The target population for the study was 480 teachers from public secondary schools and the study sample size was 214 teachers who were sampled through stratified random sampling technique. The study also had key-informants who were selected using purposive sampling technique. The study used descriptive statistical analysis. In analyzing the quantitative data the study used descriptive statistics using calculator and excel sheet while qualitative data was analyzed using content analysis. The study established that ICTs were useful in lesson planning, addressing the teacher student ratio challenges and bringing the content gap. However, majority of the Public Secondary Schools in Githunguri Sub-County still lacked facilities equipped with ICT communication tools. The major factors discovered to be influencing e-learning included; availability of computers and requisite infrastructure, teachers’ competence in use of ICT to deliver the curriculum, integration of ICT in teaching and learning, availability of technical support, top management support to e-learning using communication through ICT and availability of financial resources. The study recommends that the management of the public secondary schools should allocate funds to facilitate teachers training in ICT. The government through the ministry of education should scale up the use of communication through ICT in promoting e-learning. The ministry of education should strive to put the requisite ICT infrastructure in majority of the public secondary schools. The government and relevant stakeholder should review the ICT policy and other related education policies with a view to ensuring that e-learning is student-centered.